Which amendment repealed Prohibition?

The 21st Amendment is the correct choice as it explicitly repealed Prohibition, which was established by the 18th Amendment. Ratified in 1933, the 21st Amendment overturned the national ban on the manufacture, sale, and transportation of alcoholic beverages, allowing states to control these activities again. This marked a significant shift in American policy regarding alcohol, signaling a recognition of the challenges and unintended consequences that Prohibition had created, such as the rise of black markets and organized crime.

The other amendments listed do not have any connection to Prohibition. The 19th Amendment granted women the right to vote, the 20th Amendment dealt with the terms of office for the President and Congress, and the 22nd Amendment established term limits for the Presidency. Each of these amendments addresses different aspects of American governance and civil rights, but none are related to the repeal of Prohibition.